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Comparison of microsatellite instability detection by immunohistochemistry and molecular techniques in colorectal and endometrial cancer

DNA mismatch repair deficiency (dMMR) testing is crucial for diagnosing Lynch syndrome and detection of microsatellite unstable (MSI) tumors eligible for immunotherapy. The aim of this study was to compare the relative diagnostic performance of three molecular MSI assays: polymerase chain reaction (...

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Publicado en:Sci Rep
Autores principales: Dedeurwaerdere, Franceska, Claes, Kathleen BM, Van Dorpe, Jo, Rottiers, Isabelle, Van der Meulen, Joni, Breyne, Joke, Swaerts, Koen, Martens, Geert
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213758/
https://ncbi.nlm.nih.gov/pubmed/34145315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91974-x
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