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Identifying Optimal Loci for the Molecular Diagnosis of Microsatellite Instability

BACKGROUND: Microsatellite instability (MSI) predicts oncological response to checkpoint blockade immunotherapies. Although microsatellite mutation is pathognomonic for the condition, loci have unequal diagnostic value for predicting MSI within and across cancer types. METHODS: To better inform mole...

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Bibliografische gegevens
Gepubliceerd in:Clin Chem
Hoofdauteurs: Long, Dustin R, Waalkes, Adam, Panicker, Varun P, Hause, Ronald J, Salipante, Stephen J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528407/
https://ncbi.nlm.nih.gov/pubmed/33001187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/clinchem/hvaa177
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