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Identifying Optimal Loci for the Molecular Diagnosis of Microsatellite Instability

BACKGROUND: Microsatellite instability (MSI) predicts oncological response to checkpoint blockade immunotherapies. Although microsatellite mutation is pathognomonic for the condition, loci have unequal diagnostic value for predicting MSI within and across cancer types. METHODS: To better inform mole...

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Publicado en:Clin Chem
Main Authors: Long, Dustin R, Waalkes, Adam, Panicker, Varun P, Hause, Ronald J, Salipante, Stephen J
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528407/
https://ncbi.nlm.nih.gov/pubmed/33001187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/clinchem/hvaa177
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