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Accurate pan-cancer molecular diagnosis of microsatellite instability by single molecule molecular inversion probe capture and high throughput sequencing
BACKGROUND: Microsatellite instability (MSI) is an emerging, actionable phenotype in oncology that informs tumor response to immune checkpoint pathway immunotherapy. However, there remains a need for MSI diagnostics that are low cost, highly accurate, and generalizable across cancer types. We develo...
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| Udgivet i: | Clin Chem |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6190826/ https://ncbi.nlm.nih.gov/pubmed/29632127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2017.285981 |
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