Microsatellite instability in prostate cancer by PCR or next-generation sequencing

BACKGROUND: Microsatellite instability (MSI) is now being used as a sole biomarker to guide immunotherapy treatment for men with advanced prostate cancer. Yet current molecular diagnostic tests for MSI have not been evaluated for use in prostate cancer. METHODS: We evaluated two next-generation sequ...

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Veröffentlicht in:J Immunother Cancer
Hauptverfasser: Hempelmann, Jennifer A., Lockwood, Christina M., Konnick, Eric Q., Schweizer, Michael T., Antonarakis, Emmanuel S., Lotan, Tamara L., Montgomery, Bruce, Nelson, Peter S., Klemfuss, Nola, Salipante, Stephen J., Pritchard, Colin C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904988/
https://ncbi.nlm.nih.gov/pubmed/29665853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0341-y
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