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Ultrasensitive detection of chimerism by single-molecule molecular inversion probe capture and high throughput sequencing of copy number deletion polymorphisms

BACKGROUND: Genomic chimerism, the co-occurrence of cells from different genetic origins, provides important diagnostic information in diverse clinical contexts, including graft injury detection and longitudinal surveillance of hematopoietic stem cell transplantation patients, but existing assays ar...

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Publicado en:Clin Chem
Main Authors: Wu, David, Waalkes, Adam, Penewit, Kelsi, Salipante, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263032/
https://ncbi.nlm.nih.gov/pubmed/29549183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2017.284737
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