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Mustache: multi-scale detection of chromatin loops from Hi-C and Micro-C maps using scale-space representation

We present Mustache, a new method for multi-scale detection of chromatin loops from Hi-C and Micro-C contact maps. Mustache employs scale-space theory, a technical advance in computer vision, to detect blob-shaped objects in contact maps. Mustache is scalable to kilobase-resolution maps and reports...

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Publicat a:Genome Biol
Autors principals: Roayaei Ardakany, Abbas, Gezer, Halil Tuvan, Lonardi, Stefano, Ay, Ferhat
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528378/
https://ncbi.nlm.nih.gov/pubmed/32998764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02167-0
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