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The acidic tumor microenvironment drives a stem-like phenotype in melanoma cells
ABSTRACT: Acidosis characterizes the microenvironment of most solid tumors and is considered a new hallmark of cancer. It is mainly caused by both “aerobic” and “anaerobic” glycolysis of differently adapted cancer cells, with the final product lactic acid being responsible of the extracellular acidi...
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Publicado no: | J Mol Med (Berl) |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer Berlin Heidelberg
2020
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7525286/ https://ncbi.nlm.nih.gov/pubmed/32803272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01959-y |
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