The acidic tumor microenvironment drives a stem-like phenotype in melanoma cells

ABSTRACT: Acidosis characterizes the microenvironment of most solid tumors and is considered a new hallmark of cancer. It is mainly caused by both “aerobic” and “anaerobic” glycolysis of differently adapted cancer cells, with the final product lactic acid being responsible of the extracellular acidi...

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Bibliografski detalji
Izdano u:J Mol Med (Berl)
Glavni autori: Andreucci, Elena, Peppicelli, Silvia, Ruzzolini, Jessica, Bianchini, Francesca, Biagioni, Alessio, Papucci, Laura, Magnelli, Lucia, Mazzanti, Benedetta, Stecca, Barbara, Calorini, Lido
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2020
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525286/
https://ncbi.nlm.nih.gov/pubmed/32803272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01959-y
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