The acidic tumor microenvironment drives a stem-like phenotype in melanoma cells

ABSTRACT: Acidosis characterizes the microenvironment of most solid tumors and is considered a new hallmark of cancer. It is mainly caused by both “aerobic” and “anaerobic” glycolysis of differently adapted cancer cells, with the final product lactic acid being responsible of the extracellular acidi...

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發表在:J Mol Med (Berl)
Main Authors: Andreucci, Elena, Peppicelli, Silvia, Ruzzolini, Jessica, Bianchini, Francesca, Biagioni, Alessio, Papucci, Laura, Magnelli, Lucia, Mazzanti, Benedetta, Stecca, Barbara, Calorini, Lido
格式: Artigo
語言:Inglês
出版: Springer Berlin Heidelberg 2020
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525286/
https://ncbi.nlm.nih.gov/pubmed/32803272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01959-y
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