The acidic tumor microenvironment drives a stem-like phenotype in melanoma cells

ABSTRACT: Acidosis characterizes the microenvironment of most solid tumors and is considered a new hallmark of cancer. It is mainly caused by both “aerobic” and “anaerobic” glycolysis of differently adapted cancer cells, with the final product lactic acid being responsible of the extracellular acidi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Mol Med (Berl)
Egile Nagusiak: Andreucci, Elena, Peppicelli, Silvia, Ruzzolini, Jessica, Bianchini, Francesca, Biagioni, Alessio, Papucci, Laura, Magnelli, Lucia, Mazzanti, Benedetta, Stecca, Barbara, Calorini, Lido
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Berlin Heidelberg 2020
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525286/
https://ncbi.nlm.nih.gov/pubmed/32803272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01959-y
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