Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke

Monocyte-derived and tissue-resident macrophages are ontogenetically distinct components of the innate immune system. Assessment of their respective functions in pathology is complicated by changes to the macrophage phenotype during inflammation. Here, we find that Cxcr4-CreER enables permanent gene...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Neurosci
Egile Nagusiak: Werner, Yves, Mass, Elvira, Ashok Kumar, Praveen, Ulas, Thomas, Händlers, Kristian, Horne, Arik, Klee, Kathrin, Lupp, Amelie, Schütz, Dagmar, Saaber, Friederike, Redecker, Christoph, Schultze, Joachim L., Geissmann, Frederic, Stumm, Ralf
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523735/
https://ncbi.nlm.nih.gov/pubmed/32042176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-020-0585-y
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