The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons

Biallelic mutations in DONSON, an essential gene encoding for a replication fork protection factor, were linked to skeletal abnormalities and microcephaly. To better understand DONSON function in corticogenesis, we characterized Donson expression and consequences of conditional Donson deletion in th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Genet
Prif Awduron: Venkataramanappa, Sathish, Schütz, Dagmar, Saaber, Friederike, Kumar, Praveen Ashok, Abe, Philipp, Schulz, Stefan, Stumm, Ralf
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2021
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011756/
https://ncbi.nlm.nih.gov/pubmed/33739968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009441
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