Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke

Monocyte-derived and tissue-resident macrophages are ontogenetically distinct components of the innate immune system. Assessment of their respective functions in pathology is complicated by changes to the macrophage phenotype during inflammation. Here, we find that Cxcr4-CreER enables permanent gene...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nat Neurosci
Main Authors: Werner, Yves, Mass, Elvira, Ashok Kumar, Praveen, Ulas, Thomas, Händlers, Kristian, Horne, Arik, Klee, Kathrin, Lupp, Amelie, Schütz, Dagmar, Saaber, Friederike, Redecker, Christoph, Schultze, Joachim L., Geissmann, Frederic, Stumm, Ralf
Formato: Artigo
Idioma:Inglês
Publicado: 2020
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523735/
https://ncbi.nlm.nih.gov/pubmed/32042176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-020-0585-y
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares