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Ebselen, disulfiram, carmofur, PX-12, tideglusib, and shikonin are non-specific promiscuous SARS-CoV-2 main protease inhibitors

There is an urgent need for vaccines and antiviral drugs to combat the COVID-19 pandemic. Encouraging progress has been made in developing antivirals targeting SARS-CoV-2, the etiological agent of COVID-19. Among the drug targets being investigated, the viral main protease (M(pro)) is one of the mos...

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Podrobná bibliografie
Vydáno v:bioRxiv
Hlavní autoři: Ma, Chunlong, Hu, Yanmei, Townsend, Julia Alma, Lagarias, Panagiotis I., Marty, Michael Thomas, Kolocouris, Antonios, Wang, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523112/
https://ncbi.nlm.nih.gov/pubmed/32995786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.09.15.299164
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