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Rabgap1 promotes recycling of active β1 integrins to support effective cell migration

Integrin function depends on the continuous internalization of integrins and their subsequent endosomal recycling to the plasma membrane to drive adhesion dynamics, cell migration and invasion. Here we assign a pivotal role for Rabgap1 (GAPCenA) in the recycling of endocytosed active β1 integrins to...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Samarelli, Anna V., Ziegler, Tilman, Meves, Alexander, Fässler, Reinhard, Böttcher, Ralph T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522031/
https://ncbi.nlm.nih.gov/pubmed/32843574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.243683
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