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Rabgap1 promotes recycling of active β1 integrins to support effective cell migration

Integrin function depends on the continuous internalization of integrins and their subsequent endosomal recycling to the plasma membrane to drive adhesion dynamics, cell migration and invasion. Here we assign a pivotal role for Rabgap1 (GAPCenA) in the recycling of endocytosed active β1 integrins to...

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Bibliografiske detaljer
Udgivet i:J Cell Sci
Main Authors: Samarelli, Anna V., Ziegler, Tilman, Meves, Alexander, Fässler, Reinhard, Böttcher, Ralph T.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522031/
https://ncbi.nlm.nih.gov/pubmed/32843574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.243683
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