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Kinetics of receptor tyrosine kinase activation define ERK signaling dynamics

In responses to activation of receptor tyrosine kinases (RTKs), crucial cell fate decisions depend on the duration and dynamics of ERK signaling. In PC12 cells, epidermal growth factor (EGF) induces transient ERK activation that leads to cell proliferation, whereas nerve growth factor (NGF) promotes...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Signal
Prif Awduron: Kiyatkin, Anatoly, van Alderwerelt van Rosenburgh, Iris K., Klein, Daryl E., Lemmon, Mark A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521189/
https://ncbi.nlm.nih.gov/pubmed/32817373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaz5267
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