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Cell signaling by receptor-tyrosine kinases

Recent structural studies of receptor tyrosine kinases (RTKs) have revealed unexpected diversity in the mechanisms of their activation by growth factor ligands. Strategies for inducing dimerization by ligand binding are surprisingly diverse, as are mechanisms that couple this event to activation of...

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Detalhes bibliográficos
Main Authors: Lemmon, Mark A., Schlessinger, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914105/
https://ncbi.nlm.nih.gov/pubmed/20602996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.06.011
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