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Receptor Tyrosine Kinases with Intracellular Pseudokinase Domains

As with other groups of protein kinases, approximately 10% of the receptor tyrosine kinases (RTKs) in the human proteome contain intracellular pseudokinases that lack one or more conserved catalytically important residues. These include ErbB3, a member of the epidermal growth factor receptor (EGFR)...

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Detalhes bibliográficos
Main Authors: Mendrola, Jeannine M., Shi, Fumin, Park, Jin H., Lemmon, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777422/
https://ncbi.nlm.nih.gov/pubmed/23863174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20130104
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