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Assessing the range of kinase autoinhibition mechanisms in the insulin receptor family
To investigate the range of autoinhibitory mechanisms used by TKDs (tyrosine kinase domains) from the insulin receptor family of RTKs (receptor tyrosine kinases), we determined crystal structures of TKDs from TrkA (tropomyosin receptor kinase A, a nerve growth factor receptor) and Ror2 (receptor tyr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3492919/ https://ncbi.nlm.nih.gov/pubmed/22992069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20121365 |
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