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Kinetics of receptor tyrosine kinase activation define ERK signaling dynamics
In responses to activation of receptor tyrosine kinases (RTKs), crucial cell fate decisions depend on the duration and dynamics of ERK signaling. In PC12 cells, epidermal growth factor (EGF) induces transient ERK activation that leads to cell proliferation, whereas nerve growth factor (NGF) promotes...
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| Publicado no: | Sci Signal |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7521189/ https://ncbi.nlm.nih.gov/pubmed/32817373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaz5267 |
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