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Kinetics of receptor tyrosine kinase activation define ERK signaling dynamics
In responses to activation of receptor tyrosine kinases (RTKs), crucial cell fate decisions depend on the duration and dynamics of ERK signaling. In PC12 cells, epidermal growth factor (EGF) induces transient ERK activation that leads to cell proliferation, whereas nerve growth factor (NGF) promotes...
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| Foilsithe in: | Sci Signal |
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| Main Authors: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2020
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7521189/ https://ncbi.nlm.nih.gov/pubmed/32817373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaz5267 |
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