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Development of a convergent enantioselective synthetic route to (−)-myrocin G
The myrocins are a family of antiproliferative antibiotic fungal metabolites possessing a masked electrophilic cyclopropane. Preliminary chemical reactivity studies imputed the bioactivity of these natural products to a DNA cross-linking mechanism, but this hypothesis was not confirmed by studies wi...
Gardado en:
| Publicado en: | J Org Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7520802/ https://ncbi.nlm.nih.gov/pubmed/32615040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.0c00891 |
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