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Modeling the function of BAX and BAK in early human brain development using iPSC-derived systems
Intrinsic apoptosis relies on the ability of the BCL-2 family to induce the formation of pores on the outer mitochondrial membrane. Previous studies have shown that both BAX and BAK are essential during murine embryogenesis, and reports in human cancer cell lines identified non-canonical roles for B...
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| Pubblicato in: | Cell Death Dis |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7519160/ https://ncbi.nlm.nih.gov/pubmed/32978370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03002-x |
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