A Dysregulated DNA Methylation Landscape Linked to Gene Expression in MLL-Rearranged AML

Translocations of the KMT2A (MLL) gene define a biologically distinct and clinically aggressive subtype of acute myeloid leukaemia (AML), marked by a characteristic gene expression profile and few cooperating mutations. Although dysregulation of the epigenetic landscape in this leukaemia is particul...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Koldobskiy, Michael A., Abante, Jordi, Jenkinson, Garrett, Pujadas, Elisabet, Tetens, Ashley, Zhao, Feifei, Tryggvadottir, Rakel, Idrizi, Adrian, Reinisch, Andreas, Majeti, Ravindra, Goutsias, John, Feinberg, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518694/
https://ncbi.nlm.nih.gov/pubmed/32114880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2020.1734149
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