A Dysregulated DNA Methylation Landscape Linked to Gene Expression in MLL-Rearranged AML

Translocations of the KMT2A (MLL) gene define a biologically distinct and clinically aggressive subtype of acute myeloid leukaemia (AML), marked by a characteristic gene expression profile and few cooperating mutations. Although dysregulation of the epigenetic landscape in this leukaemia is particul...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Epigenetics
Prif Awduron: Koldobskiy, Michael A., Abante, Jordi, Jenkinson, Garrett, Pujadas, Elisabet, Tetens, Ashley, Zhao, Feifei, Tryggvadottir, Rakel, Idrizi, Adrian, Reinisch, Andreas, Majeti, Ravindra, Goutsias, John, Feinberg, Andrew P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2020
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518694/
https://ncbi.nlm.nih.gov/pubmed/32114880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2020.1734149
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