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Ranking genomic features using an information-theoretic measure of epigenetic discordance

BACKGROUND: Establishment and maintenance of DNA methylation throughout the genome is an important epigenetic mechanism that regulates gene expression whose disruption has been implicated in human diseases like cancer. It is therefore crucial to know which genes, or other genomic features of interes...

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Publicat a:BMC Bioinformatics
Autors principals: Jenkinson, Garrett, Abante, Jordi, Koldobskiy, Michael A., Feinberg, Andrew P., Goutsias, John
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454630/
https://ncbi.nlm.nih.gov/pubmed/30961526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2777-6
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