A genome-wide pooled shRNA screen identifies PPP2R2A as a predictive biomarker for the response to ATR and CHK1 inhibitors

There is currently a lack of precise predictive biomarkers for patient selection in clinical trials of inhibitors targeting replication stress (RS) response proteins ATR and CHK1. The objective of this study was to identify novel predictive biomarkers for the response to these agents in treating non...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cancer Res
Autors principals: Qiu, Zhaojun, Fa, Pengyan, Liu, Tao, Prasad, Chandra B., Ma, Shanhuai, Hong, Zhipeng, Chan, Ernest R., Wang, Hongbing, Li, Zaibo, He, Kai, Wang, Qi-En, Williams, Terence M., Yan, Chunhong, Sizemore, Steven T., Narla, Goutham, Zhang, Junran
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518641/
https://ncbi.nlm.nih.gov/pubmed/32522823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-0057
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars