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Lack of Interferon (IFN) Response to T7 Transcribed pppG (n)(n = 2,3)-shRNA
RNA interference (RNAi) mediated by siRNAs has proved to be a highly effective gene silencing mechanism with great potential for gene therapeutic applications. However, siRNA agents have been shown to exert non-target-related biological effects and toxicities, including immune stimulation. Specifica...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2403744/ https://ncbi.nlm.nih.gov/pubmed/18066904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15257770701503647 |
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