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Lack of Interferon (IFN) Response to T7 Transcribed pppG (n)(n = 2,3)-shRNA

RNA interference (RNAi) mediated by siRNAs has proved to be a highly effective gene silencing mechanism with great potential for gene therapeutic applications. However, siRNA agents have been shown to exert non-target-related biological effects and toxicities, including immune stimulation. Specifica...

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Sonraí Bibleagrafaíochta
Main Authors: Gondai, Takuma, Yamaguchi, Kazuya, Hashimoto, Kahoko, Miyano-Kurosaki, Naoko, Takaku, Hiroshi
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis Group 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2403744/
https://ncbi.nlm.nih.gov/pubmed/18066904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15257770701503647
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