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A role of the CTCF binding site at enhancer Eα in the dynamic chromatin organization of the Tcra–Tcrd locus

The regulation of T cell receptor Tcra gene rearrangement has been extensively studied. The enhancer Eα plays an essential role in Tcra rearrangement by establishing a recombination centre in the Jα array and a chromatin hub for interactions between Vα and Jα genes. But the mechanism of the Eα and i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Zhao, Hao, Li, Zhaoqiang, Zhu, Yongchang, Bian, Shasha, Zhang, Yan, Qin, Litao, Naik, Abani Kanta, He, Jiangtu, Zhang, Zhenhai, Krangel, Michael S, Hao, Bingtao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515734/
https://ncbi.nlm.nih.gov/pubmed/32853367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa711
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