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Tcrd rearrangement redirects a processive Tcra recombination program to expand the Tcra repertoire
Adaptive immunity depends on diverse T cell receptor repertoires generated by V(D)J recombination. Here, we define the principles by which combinatorial diversity is generated in the murine Tcra repertoire. Tcra and Tcrd gene segments share the Tcra-Tcrd locus, with interspersed V(α) and V(δ) segmen...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5529038/ https://ncbi.nlm.nih.gov/pubmed/28591585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.045 |
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