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A discrete chromatin loop in the murine Tcra-Tcrd locus shapes the TCRδ and TCRα repertoires
The Tcra-Tcrd locus undergoes V(D)J recombination in CD4(−)CD8(−)double-negative thymocytes and CD4(+)CD8(+) double-positive thymocytes to generate diverse TCRδ and TCRα repertoires, respectively. Here we reveal a Tcra-Tcrd locus chromatin interaction network in double-negative thymocytes that was f...
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| Publicat a: | Nat Immunol |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4575630/ https://ncbi.nlm.nih.gov/pubmed/26258942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3232 |
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