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Specification of Vδ and Vα usage by Tcra/Tcrd locus V gene segment promoters,2
The Tcra/Tcrd locus undergoes V-Dδ-Jδ rearrangement in CD4(−)CD8(−) thymocytes to form the TCRδ chain of the γδ TCR and V-Jα rearrangement in CD4(+)CD8(+) thymocytes to form the TCRα chain of the αβ TCR. Most V segments in the locus participate in V-Jα rearrangement, but only a small and partially o...
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| Published in: | J Immunol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4282949/ https://ncbi.nlm.nih.gov/pubmed/25472997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402423 |
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