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Regulation of Tcra gene assembly by a complex hierarchy of germline J(α) promoters

Tcra gene assembly is characterized by an orderly progression of primary and secondary V(α) to J(α) recombination events across the J(α) array, but the targeting mechanisms responsible for this progression are largely unknown. Previous studies revealed that the TEA promoter plays an important role i...

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Autori principali: Hawwari, Abbas, Bock, Cheryl, Krangel, Michael S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413064/
https://ncbi.nlm.nih.gov/pubmed/15806105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1189
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