Tcrd rearrangement redirects a processive Tcra recombination program to expand the Tcra repertoire

Adaptive immunity depends on diverse T cell receptor repertoires generated by V(D)J recombination. Here, we define the principles by which combinatorial diversity is generated in the murine Tcra repertoire. Tcra and Tcrd gene segments share the Tcra-Tcrd locus, with interspersed V(α) and V(δ) segmen...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Carico, Zachary M., Roy Choudhury, Kingshuk, Zhang, Baojun, Zhuang, Yuan, Krangel, Michael S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529038/
https://ncbi.nlm.nih.gov/pubmed/28591585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.045
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