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Conformational flexibility and oligomerization of BRCA2 regions induced by RAD51 interaction
BRCA2 is a key breast cancer associated protein that is predicted to have interspersed regions of intrinsic disorder. Intrinsic disorder coupled with large size likely allows BRCA2 to sample a broad range of conformational space. We expect that the resulting dynamic arrangements of BRCA2 domains are...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7515699/ https://ncbi.nlm.nih.gov/pubmed/32785644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa648 |
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