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Caffeine suppresses homologous recombination through interference with RAD51-mediated joint molecule formation
Caffeine is a widely used inhibitor of the protein kinases that play a central role in the DNA damage response. We used chemical inhibitors and genetically deficient mouse embryonic stem cell lines to study the role of DNA damage response in stable integration of the transfected DNA and found that c...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3711438/ https://ncbi.nlm.nih.gov/pubmed/23666627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt375 |
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