Architectural plasticity of human BRCA2–RAD51 complexes in DNA break repair

The tumor suppressor BRCA2 is a large multifunctional protein mutated in 50–60% of familial breast cancers. BRCA2 interacts with many partners and includes multiple regions with potentially disordered structure. In homology directed DNA repair BRCA2 delivers RAD51 to DNA resulting in removal of RPA...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Sánchez, Humberto, Paul, Maarten W., Grosbart, Małgorzata, van Rossum-Fikkert, Sarah E., Lebbink, Joyce H. G., Kanaar, Roland, Houtsmuller, Adriaan B., Wyman, Claire
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416905/
https://ncbi.nlm.nih.gov/pubmed/28168276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx084
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados