Analysis of circulating DNA and protein biomarkers to predict the clinical activity of regorafenib and assess prognosis in patients with metastatic colorectal cancer: a retrospective, exploratory analysis of the CORRECT trial

BACKGROUND: Tumour mutational status is an important determinant of the response of metastatic colorectal cancer to targeted treatments. However, the genotype of the tissue obtained at the time of diagnosis might not accurately represent tumour genotype after multiple lines of treatment. This retros...

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書誌詳細
出版年:Lancet Oncol
主要な著者: Tabernero, Josep, Lenz, Heinz-Josef, Siena, Salvatore, Sobrero, Alberto, Falcone, Alfredo, Ychou, Marc, Humblet, Yves, Bouché, Olivier, Mineur, Laurent, Barone, Carlo, Adenis, Antoine, Yoshino, Takayuki, Goldberg, Richard M, Sargent, Daniel J, Wagner, Andrea, Laurent, Dirk, Teufel, Michael, Jeffers, Michael, Grothey, Axel, Van Cutsem, Eric
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7513622/
https://ncbi.nlm.nih.gov/pubmed/26184520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(15)00138-2
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