Analysis of circulating DNA and protein biomarkers to predict the clinical activity of regorafenib and assess prognosis in patients with metastatic colorectal cancer: a retrospective, exploratory analysis of the CORRECT trial

BACKGROUND: Tumour mutational status is an important determinant of the response of metastatic colorectal cancer to targeted treatments. However, the genotype of the tissue obtained at the time of diagnosis might not accurately represent tumour genotype after multiple lines of treatment. This retros...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Lancet Oncol
Prif Awduron: Tabernero, Josep, Lenz, Heinz-Josef, Siena, Salvatore, Sobrero, Alberto, Falcone, Alfredo, Ychou, Marc, Humblet, Yves, Bouché, Olivier, Mineur, Laurent, Barone, Carlo, Adenis, Antoine, Yoshino, Takayuki, Goldberg, Richard M, Sargent, Daniel J, Wagner, Andrea, Laurent, Dirk, Teufel, Michael, Jeffers, Michael, Grothey, Axel, Van Cutsem, Eric
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7513622/
https://ncbi.nlm.nih.gov/pubmed/26184520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(15)00138-2
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