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A 3D brain unit model to further improve prediction of local drug distribution within the brain
The development of drugs targeting the brain still faces a high failure rate. One of the reasons is a lack of quantitative understanding of the complex processes that govern the pharmacokinetics (PK) of a drug within the brain. While a number of models on drug distribution into and within the brain...
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| Vydáno v: | PLoS One |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7511021/ https://ncbi.nlm.nih.gov/pubmed/32966285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0238397 |
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