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The mastermind approach to CNS drug therapy: translational prediction of human brain distribution, target site kinetics, and therapeutic effects

Despite enormous advances in CNS research, CNS disorders remain the world’s leading cause of disability. This accounts for more hospitalizations and prolonged care than almost all other diseases combined, and indicates a high unmet need for good CNS drugs and drug therapies. Following dosing, not on...

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Autore principale: de Lange, Elizabeth CM
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602026/
https://ncbi.nlm.nih.gov/pubmed/23432852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-10-12
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