Application of intracerebral microdialysis to study regional distribution kinetics of drugs in rat brain.

1. The purpose of the present study was to determine whether intracerebral microdialysis can be used for the assessment of local differences in drug concentrations within the brain. 2. Two transversal microdialysis probes were implanted in parallel into the frontal cortex of male Wistar rats, and us...

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Autores principales: de Lange, E. C., Bouw, M. R., Mandema, J. W., Danhof, M., de Boer, A. G., Breimer, D. D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909064/
https://ncbi.nlm.nih.gov/pubmed/8581296
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