The Blood-Brain Barrier: Clinical Implications for Drug Delivery to the Brain

The blood-brain barrier (BBB) determines whether or not a given drug can reach the central nervous system (CNS), either by passive diffusion or through carrier or receptor systems. Initial work focused on the structural and physico-chemical requirements favouring transport across the BBB as related...

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Bibliographic Details
Published in:J R Coll Physicians Lond
Main Authors: De Boer, A G, Breimer, D D
Format: Artigo
Language:Inglês
Published: Royal College of Physicians of London 1994
Subjects:
Overviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5401103/
https://ncbi.nlm.nih.gov/pubmed/7884704
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