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The need for mathematical modelling of spatial drug distribution within the brain
The blood brain barrier (BBB) is the main barrier that separates the blood from the brain. Because of the BBB, the drug concentration-time profile in the brain may be substantially different from that in the blood. Within the brain, the drug is subject to distributional and elimination processes: di...
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| Pubblicato in: | Fluids Barriers CNS |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6521438/ https://ncbi.nlm.nih.gov/pubmed/31092261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-019-0133-x |
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