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Modeling the Effect of Binding Kinetics in Spatial Drug Distribution in the Brain
A 3-dimensional mathematical model is developed to determine the effect of drug binding kinetics on the spatial distribution of a drug within the brain. The key components, namely, transport across the blood-brain barrier (BBB), drug distribution in the brain extracellular fluid (ECF), and drug bind...
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| Udgivet i: | Comput Math Methods Med |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Hindawi
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8275424/ https://ncbi.nlm.nih.gov/pubmed/34285707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5533886 |
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