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A 3D brain unit model to further improve prediction of local drug distribution within the brain

The development of drugs targeting the brain still faces a high failure rate. One of the reasons is a lack of quantitative understanding of the complex processes that govern the pharmacokinetics (PK) of a drug within the brain. While a number of models on drug distribution into and within the brain...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Vendel, Esmée, Rottschäfer, Vivi, de Lange, Elizabeth C. M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511021/
https://ncbi.nlm.nih.gov/pubmed/32966285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0238397
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