Hypothalamic CDK4 regulates thermogenesis by modulating sympathetic innervation of adipose tissues

This study investigated the role of CDK4 in the oxidative metabolism of brown adipose tissue (BAT). BAT from Cdk4 (−/−) mice exhibited fewer lipids and increased mitochondrial volume and expression of canonical thermogenic genes, rendering these mice more resistant to cold exposure. Interestingly, t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:EMBO Rep
मुख्य लेखकों: Castillo‐Armengol, Judit, Barquissau, Valentin, Geller, Sarah, Ji, Honglei, Severi, Ilenia, Venema, Wiebe, Fenandez, Eric Aria, Moret, Catherine, Huber, Katharina, Leal‐Esteban, Lucia C, Nasrallah, Anita, Martinez‐Carreres, Laia, Niederhäuser, Guy, Seoane‐Collazo, Patricia, Lagarrigue, Sylviane, López, Miguel, Giordano, Antonio, Croizier, Sophie, Thorens, Bernard, Lopez‐Mejia, Isabel C, Fajas, Lluis
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2020
विषय:
Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7507572/
https://ncbi.nlm.nih.gov/pubmed/32657019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949807
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