CDK7 Mediates the Beta-Adrenergic Signaling in Thermogenic Brown and White Adipose Tissues

Cyclin-dependent kinases (CDKs) are emerging regulators of adipose tissue metabolism. Here we aimed to explore the role of CDK7 in thermogenic fat. We found that CDK7 brown adipose tissue (BAT)-specific knockout mice (Cdk7(bKO)) have decreased BAT mass and impaired β3-adrenergic signaling and develo...

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Publicado no:iScience
Main Authors: Ji, Honglei, Chen, Yizhe, Castillo-Armengol, Judit, Dreos, René, Moret, Catherine, Niederhäuser, Guy, Delacuisine, Brigitte, Lopez-Mejia, Isabel C., Denechaud, Pierre-Damien, Fajas, Lluis
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7256631/
https://ncbi.nlm.nih.gov/pubmed/32464595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101163
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