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CDK7 Mediates the Beta-Adrenergic Signaling in Thermogenic Brown and White Adipose Tissues
Cyclin-dependent kinases (CDKs) are emerging regulators of adipose tissue metabolism. Here we aimed to explore the role of CDK7 in thermogenic fat. We found that CDK7 brown adipose tissue (BAT)-specific knockout mice (Cdk7(bKO)) have decreased BAT mass and impaired β3-adrenergic signaling and develo...
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| Yayımlandı: | iScience |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7256631/ https://ncbi.nlm.nih.gov/pubmed/32464595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101163 |
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